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Information on Protocol P-1


Breast Cancer Prevention Trial Speakers' Biographies

Norman Wolmark, M.D. is the Chairman of the National Surgical Adjuvant Breast and Bowel Project (NSABP), a cooperative clinical trials group funded primarily by the National Cancer Institute. Dr. Wolmark is also the Principal Investigator of the NSABP Operations Center located on the Allegheny campus of Allegheny University of the Health Sciences.

Dr. Wolmark received his bachelor's and medical degrees from McGill University in Montreal, Canada. After completing his surgical residency at the University of Pittsburgh, he received additional fellowship training in surgical oncology at the National Cancer Institute in Bethesda, Maryland, and at the Memorial Sloan-Kettering Cancer Center in New York City, New York. He is currently Professor and Chairman of the Department of Human Oncology at Allegheny University of Health Sciences.


D. Lawrence Wickerham, M.D. has been the Associate Chairman of the NSABP since 1995 and is the Protocol Officer for the Breast Cancer Prevention Trial. As the Protocol Officer, Dr. Wickerham oversees the conduct and medical review of the protocol and coordinates committee activities. Dr. Wickerham has worked for the NSABP in several capacities since 1981.

Dr. Wickerham received his bachelor's degree from Washington and Jefferson College in Washington, Pennsylvania, and received his medical degree from the University of Pittsburgh. He is also currently an Associate Professor of Human Oncology at the Allegheny campus of the Allegheny University of the Health Sciences.


Bernard Fisher, M.D. is a founding member and former chairperson of the NSABP from 1967 to 1994. He has devoted his career to exploring the biology of cancer and providing new treatments for women with breast cancer. Dr. Fisher's laboratory and clinical investigations have resulted in major alterations in the use of surgery and systemic therapy for breast cancer management.

Beginning in 1990, Dr. Fisher and his NSABP colleagues, working with the NCI and numerous government agencies, designed and implemented the first breast cancer prevention trial in the United States. In addition to determining the value of tamoxifen in breast cancer prevention, the study was to be directed toward addressing questions related to the genetics of the disease. Dr. Fisher is past-president of the American Society of Clinical Oncology and a former member of both the President's Cancer Panel and the National Cancer Advisory Board. He is currently Scientific Director of the NSABP and professor at the Allegheny campus of the Allegheny University of the Health Sciences.


H. Samuel Wieand, Ph.D. has been the Director of the NSABP Biostatistical Department since 1995. He is also a Professor in and the Associate Chairman of the Department of Biostatistics at the University of Pittsburgh. Prior to joining the NSABP, he was Director of Biostatistics of the Mayo Clinic Cancer Center and of the North Central Cancer Treatment Group (NCCTG).

Dr. Wieand received his Ph.D. from the University of Maryland in 1974. He is a Fellow of the American Statistical Association.


Joseph Costantino, Dr.P.H. is the Associate Director of the NSABP Biostatistical Center and the Coordinating Statistician of the NSABP Breast Cancer Prevention Trial. He is also an Associate Professor of Biostatistics at the University of Pittsburgh's Graduate School of Public Health. Dr. Costantino has been with the NSABP and the University of Pittsburgh since 1984. Before joining the NSABP, he was employed as the Director of Health Effects Research for the BCR National Laboratory. Prior to this position, he was the Deputy Director of the Allegheny County Health Department in Pittsburgh, Pennsylvania.

Dr. Costantino received his bachelor's degree from Bethany College in Bethany, West Virginia and his doctoral degree from the University of Pittsburgh in Pittsburgh, Pennsylvania.