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NSABP Clinical Trials Overview


Protocol C-09
A Phase III Clinical Trial Comparing Oxaliplatin, Capecitabine and Hepatic Arterial Infusion of Floxuridine to Oxaliplatin and Capecitabine in Patients with Resected or Ablated Liver Metastases from Colorectal Cancer

Specific Aims
Primary Aim
The primary aim of this study is to compare progression-free interval (PFI) between the two treatment groups.

Secondary Aim
The secondary aims of this study are to:
  • compare overall survival and liver PFI between the two treatment groups;
  • assess toxicity in each of the treatment regimens;
  • compare self-reported symptoms between two treatment groups; and
  • compare quality of life in each of the treatment regimens.